Share to Facebook Share to Twitter Share to LinkedIn Pinterest Email

Einstein Image

Einstein Image

2016-einstein-img

Einstein Image

Joining the circulatory systems of an old and a young animal is called heterochronic parabiosis. Here we see a cross-section of the small intestine of a young mouse that was parabiosed to an old mouse for two months. Postdoctoral research fellow Tahmineh Tabrizian, M.D., Ph.D., has found that factors in old-mouse blood “age” intestinal stem cells in young mice by impairing their ability to proliferate. (The stem-cell damage can’t be seen in this low-magnification image.) The next step in Dr. Tabrizian’s research: Identify the stem-cell aging factors present in old blood and see whether targeting those factors (using neutralizing antibodies, for example) helps rejuvenate stem cells in old mice and, ultimately, in old people. Dr. Tabrizian’s mentor is Derek M. Huffman, Ph.D., an assistant professor of molecular pharmacology and of medicine (endocrinology).

Share to Facebook Share to Twitter Share to LinkedIn Share to Pinterest Email

The Issue at a Glance

More From Einstein

Residents Respond to COVID Surge
Freeing Immune Cells to Combat Cancer
Hispanic Health Foundation Scholarships
Dennis Shields Postdoctoral Prizes
Hispanic Heritage Month
Marmur Awards Marks 25 Years
The Women Who Battle Blood Cancer
Einstein Celebrates Black History
Einstein Students Join Vaccination Effort
Einstein Among Top in Research Funding
Match Day Video:
Class of 2021
The Einstein Difference

Content

Research Notes
Motivations: Donors & Alumni

Share

Share to Facebook Share to Twitter Share to LinkedIn Email

Past Issues

Download Magazine

Search

Subscribe

  • This field is for validation purposes and should be left unchanged.